The history of Nueva Vizcaya could still be reflected from the culture and customs of its early settlers, which included the Ilongots (now called Bugkalots), Igorots, Ifugaos, Isinais, and Gaddangs. The influx of civilization and the infusion of modern technology to the lifestream of the province induced many immigrants from the adjacent provinces, primarily Ilocanos, Tagalogs, Pangasinenses, Kapampangans, among others.

Home of the Isinais, Nueva Vizcaya is located in the northcentral part of Luzon in Region 2. It is surrounded by notable mountain ranges such as the Sierra Madre on the east, Caraballo on the south, and Cordillera on the west. The province has several principal rivers: Magat, Matuno, Marang, Sta. Fe, and Sta. Cruz. All these rivers are tributaries of the Magat River which flows into the Cagayan River. The province is bounded on the north and northeast by the province of Ifugao and Isabela, on the east and southeast by Qurino and Aurora, on the south by Nueva Ecija, and on the west by Benguet and Pangasinan.

The province is considered as one congressional district and has 15 municipalities and 274 barangays. Bayombong is the provincial capital while Solano and Kayapa are its commercial and summer capital, respectively.

The province has basically an agricultural economy with commerce, trade, and industry contributing to its growth and development. Among other major economic activities are farming and cattle and swine raising. Primary crops are palay and corn. Minor crops are rootcrops, vegetables, and fruits. The province produces quality onions and vegetables often sold in Metro Manila. Oranges and mangoes are now major crops being exported fresh to Asian countries.